Immature and mature helminths
With few exceptions, adult flukes, cestodes, and nematodes produce eggs that are passed . The segments nearest the neck are immature (sex organs not fully .
Objectives
The risk of mortality as a result of infection with helminths is for the most part low. responding to helminth products do not mature in the conventional sense. .. cell differentiation and polarizes immature dendritic cell maturation towards a Th2 .
Description:As a component of their response to pathogen-associated stimuli, DCs produce cytokines and express surface molecules that provide important cues to modulate the effector functions of responding Th cells. Much is known of how DCs respond to, and influence immune response outcome to, bacterial and viral pathogens. However, relatively little is understood about how DCs respond to helminth parasites. This is an area of considerable interest since it impacts our understanding of the initiation of Th2 responses, which are stereotypically associated with helminth infections, and the regulation of allergic and autoimmune pathologies which evidence suggests are less severe or absent in individuals infected with helminths.
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